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Central administration of palmitoylethanolamide lowers hyperalgesia in mice by way of inhibition of NF??B nuclear signalling in dorsal root ganglia. Eur J Pharmacol?acylethanolamines (NAEs), endogenous biologically active lipids such as the endogenous cannabinoid receptor ligand anandamide plus the satiety variable oleoylethanolamide. PEA was disco

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